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	Provedor de dados Genet. Mol. Biol. (3) Autor Azizi,Fereidoun (1) Daneshpour,Maryam S (1) Faria Jr,Silvio R. (1) Hedayati,Mehdi (1) Lauretto,Marcelo S. (1) Nakano,Fabio (1) Pereira,Carlos A.B. (1) Stark,Alan E. (1) Stern,Julio M. (1) Mais... Palavra-chave Hardy-Weinberg equilibrium (3) Cholesteryl ester transfer protein (CETP) (1) FBST (1) Linkage disequilibrium (1) Non-random mating (1) Polymorphisms (1) Significance tests (1) Mais... Tipo do documento Info:eu-repo/semantics/article (2) Info:eu-repo/semantics/other (1) Ano 2009 (1) 2007 (1) 2005 (1) País Brazil (3) Idioma Inglês (3)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 3 Primeira ... 1 ... Última A straightforward multiallelic significance test for the Hardy-Weinberg equilibrium law Genet. Mol. Biol. Lauretto,Marcelo S.; Nakano,Fabio; Faria Jr,Silvio R.; Pereira,Carlos A.B.; Stern,Julio M.. Much forensic inference based upon DNA evidence is made assuming Hardy-Weinberg Equilibrium (HWE) for the genetic loci being used. Several statistical tests to detect and measure deviation from HWE have been devised, and their limitations become more obvious when testing for deviation within multiallelic DNA loci. The most popular methods-Chi-square and Likelihood-ratio tests-are based on asymptotic results and cannot guarantee a good performance in the presence of low frequency genotypes. Since the parameter space dimension increases at a quadratic rate on the number of alleles, some authors suggest applying sequential methods, where the multiallelic case is reformulated as a sequence of "biallelic" tests. However, in this approach it is not obvious how... Tipo: Info:eu-repo/semantics/article Palavras-chave: Hardy-Weinberg equilibrium; Significance tests; FBST. Ano: 2009 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572009000300028 TaqI B1/B2 and -629A/C cholesteryl ester transfer protein (CETP) gene polymorphisms and their association with CETP activity and high-density lipoprotein cholesterol levels in a Tehranian population. Part of the Tehran Lipid and Glucose Study (TLGS) Genet. Mol. Biol. Daneshpour,Maryam S; Hedayati,Mehdi; Azizi,Fereidoun. We examined the cholesteryl ester transfer protein (CETP) gene TaqI intron 1 B1/B2 polymorphism and the -629A/C CETP promoter polymorphism in respect to high-density lipoprotein cholesterol (HDL-C) in a healthy Iranian population taken from the Tehran Lipid and Glucose Study (TLGS). The relationship between CETP activity and HDL-C level was also determined along with body mass index, blood pressure and tobacco smoking status. PCR-RFLP used to amplify a segment of the CETP intron 1 TaqI (B2/B1) polymorphism from 1021 individuals and we selected 345 individuals from the lowest, middle and highest HDL-C deciles and investigated the -629A/C polymorphism. We also evaluated the CETP activity of 103 of these individuals, each with at least one homozygous allele.... Tipo: Info:eu-repo/semantics/article Palavras-chave: Cholesteryl ester transfer protein (CETP); Hardy-Weinberg equilibrium; Linkage disequilibrium; Polymorphisms. Ano: 2007 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572007000600001 The Hardy-Weinberg principle Genet. Mol. Biol. Stark,Alan E.. Hardy-Weinberg genotypic proportions can be maintained in a population under non-random mating. A compact formula gives the proportions of mating pair types. These are illustrated by some simple examples. Tipo: Info:eu-repo/semantics/other Palavras-chave: Hardy-Weinberg equilibrium; Non-random mating. Ano: 2005 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572005000300027 Registros recuperados: 3 Primeira ... 1 ... Última

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